Examining the RNAi Mechanism Kit (RNAi, Amplification, and Electrophoresis Kit with Ethidium Bromide; with voucher)

Advanced - For experienced high school and college classes; requires some basic technical skill.

• Demonstrate to your students the power of silencing a single gene
• Teach about a powerful method for determining gene function
• Explore the relationship between phenotype, genotype, and RNAi-induced phenotype
• Perform bioinformatics exercises exploring protein function and C. elegans, and human relatedness

RNA interference (RNAi) is a technique that allows you to silence the expression of a chosen gene by specifically degrading the gene's mRNA. Examining the RNAi Mechanism kit allows students to use this Nobel Prize-winning technique to silence the dpy-13 gene in the nonparasitic roundworm C. elegans. They observe wild-type worms eat a lab strain of E. coli that expresses double-stranded RNA (dsRNA) corresponding to the targeted gene, dumpy 13 (dpy-13).

Kit includes a voucher to request perishable materials later at your convenience. Contact us or return the voucher to request delivery of perishables.

FREE 1-year access to digital resources that support NGSS instruction included.

   This item is sold and shipped to schools and businesses only. Not available to individuals or residential addresses. For substitution suggestions, please call us at 800.334.5551 (8am to 8pm, ET, Monday-Friday).